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Issue 7, 2012
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Designed synthesis of uniformly sized iron oxide nanoparticles for efficient magnetic resonance imaging contrast agents

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Abstract

Various magnetic nanoparticles have been extensively investigated as novel magnetic resonance imaging (MRI) contrast agents owing to their unique characteristics, including efficient contrast effects, biocompatibility, and versatile surface functionalization capability. Nanoparticles with high relaxivity are very desirable because they would increase the accuracy of MRI. Recent progress in nanotechnology enables fine control of the size, crystal structure, and surface properties of iron oxide nanoparticles. In this tutorial review, we discuss how MRI contrast effects can be improved by controlling the size, composition, doping, assembly, and surface properties of iron-oxide-based nanoparticles.

Graphical abstract: Designed synthesis of uniformly sized iron oxide nanoparticles for efficient magnetic resonance imaging contrast agents

  • This article is part of the themed collection: Nanomedicine
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Article information


Submitted
11 Sep 2011
First published
02 Dec 2011

Chem. Soc. Rev., 2012,41, 2575-2589
Article type
Tutorial Review

Designed synthesis of uniformly sized iron oxide nanoparticles for efficient magnetic resonance imaging contrast agents

N. Lee and T. Hyeon, Chem. Soc. Rev., 2012, 41, 2575
DOI: 10.1039/C1CS15248C

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