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Issue 4, 2012
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Green chemistry oriented organic synthesis in water

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The use of water as solvent features many benefits such as improving reactivities and selectivities, simplifying the workup procedures, enabling the recycling of the catalyst and allowing mild reaction conditions and protecting-group free synthesis in addition to being benign itself. In addition, exploring organic chemistry in water can lead to uncommon reactivities and selectivities complementing the organic chemists' synthetic toolbox in organic solvents. Studying chemistry in water also allows insight to be gained into Nature's way of chemical synthesis. However, using water as solvent is not always green. This tutorial review briefly discusses organic synthesis in water with a Green Chemistry perspective.

Graphical abstract: Green chemistry oriented organic synthesis in water

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The article was received on 18 Aug 2011 and first published on 02 Nov 2011

Article type: Tutorial Review
DOI: 10.1039/C1CS15222J
Chem. Soc. Rev., 2012,41, 1415-1427

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    Green chemistry oriented organic synthesis in water

    M. Simon and C. Li, Chem. Soc. Rev., 2012, 41, 1415
    DOI: 10.1039/C1CS15222J

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