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Issue 88, 2012
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A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells

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Abstract

A new ratiometric fluorescence probe E1 based on an excited-state intramolecular proton transfer (ESIPT) mechanism for detection of hydrogen sulfide (H2S) is reported. E1 responds to H2S quickly and showed a 30-fold fluorescence enhancement in 2 minutes. Moreover, E1 can detect H2S quantitatively with a detection limit as low as 0.12 μM in aqueous solution. Its potential for biological applications was confirmed by employing it for fluorescence imaging of H2S in living cells.

Graphical abstract: A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells

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Publication details

The article was received on 16 Jul 2012, accepted on 14 Sep 2012 and first published on 14 Sep 2012


Article type: Communication
DOI: 10.1039/C2CC36141H
Chem. Commun., 2012,48, 10871-10873

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    A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells

    Z. Xu, L. Xu, J. Zhou, Y. Xu, W. Zhu and X. Qian, Chem. Commun., 2012, 48, 10871
    DOI: 10.1039/C2CC36141H

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