Issue 86, 2012
From the journal:

Chemical Communications

First steps towards conformationally selective artificial lectins: the chair-boat discrimination by molecularly imprinted polymers†

Vincent Lemau de Talancé,a   Olivier Massinon,a   Rachid Baati,b   Alain Wagnerb  and  Stéphane P. Vincent*a  

* Corresponding authors

a Laboratoire de Chimie Bioorganique, Département de Chimie, FUNDP, Rue de Bruxelles, 61, Namur, Belgium
E-mail: stephane.vincent@fundp.ac.be
Fax: +32-81-724517
Tel: +32-81-724521

b Université de Strasbourg, Faculté de Pharmacie CNRS/UMR 7199, Laboratoire des Systèmes Chimiques Fonctionnels, 74 route du Rhin, 67401 Illkirch, France

Abstract

A series of molecularly imprinted polymers (MIPs) were prepared in the presence of a synthetic galactoside locked in a 1,4B boat conformation. This study demonstrates that, depending on the polymerisation technique, an organic material can selectively bind a carbohydrate in a biologically relevant boat conformation.

Graphical abstract: First steps towards conformationally selective artificial lectins: the chair-boat discrimination by molecularly imprinted polymers

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Article information

DOI
https://doi.org/10.1039/C2CC35386E
Article type
Communication
Submitted
23 Mar 2012
Accepted
03 Sep 2012
First published
04 Sep 2012

Chem. Commun., 2012,48, 10684-10686

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First steps towards conformationally selective artificial lectins: the chair-boat discrimination by molecularly imprinted polymers

V. L. D. Talancé, O. Massinon, R. Baati, A. Wagner and S. P. Vincent, Chem. Commun., 2012, 48, 10684 DOI: 10.1039/C2CC35386E

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