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Issue 62, 2012
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Remarkable photocytotoxicity of curcumin in HeLa cells in visible light and arresting its degradation on oxovanadium(IV) complex formation

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Abstract

Curcumin (Hcur) as a cellular imaging and PDT agent shows remarkable photocytotoxicity in HeLa cells in visible light of 400–700 nm giving IC50 = 8.2 ± 0.2 μM and its degradation is arrested on formation of photocytotoxic dipyridophenazine (dppz) complex [VO(cur)(dppz)Cl] (IC50 = 3.3 ± 0.4 μM), while both are less toxic in the dark.

Graphical abstract: Remarkable photocytotoxicity of curcumin in HeLa cells in visible light and arresting its degradation on oxovanadium(iv) complex formation

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Publication details

The article was received on 17 May 2012, accepted on 07 Jun 2012 and first published on 29 Jun 2012


Article type: Communication
DOI: 10.1039/C2CC33576J
Chem. Commun., 2012,48, 7702-7704

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    Remarkable photocytotoxicity of curcumin in HeLa cells in visible light and arresting its degradation on oxovanadium(IV) complex formation

    S. Banerjee, P. Prasad, A. Hussain, I. Khan, P. Kondaiah and A. R. Chakravarty, Chem. Commun., 2012, 48, 7702
    DOI: 10.1039/C2CC33576J

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