Jump to main content
Jump to site search

Issue 59, 2012
Previous Article Next Article

Imaging histamine in live basophils and macrophages with a fluorescent mesoionic acid fluoride

Author affiliations

Abstract

Histamine is a biogenic amine with fundamental roles in circulatory and immune systems. We report a fluorescent small molecule (Histamine Blue) for imaging intracellular histamine in live basophils and macrophages. Histamine Blue is a fluorescent mesoionic acid fluoride that turns on upon reaction with histamine. The selective response of Histamine Blue enabled the visualization of intracellular histamine under different physiological conditions.

Graphical abstract: Imaging histamine in live basophils and macrophages with a fluorescent mesoionic acid fluoride

Back to tab navigation

Supplementary files

Article information


Submitted
30 Mar 2012
Accepted
29 May 2012
First published
30 May 2012

Chem. Commun., 2012,48, 7401-7403
Article type
Communication

Imaging histamine in live basophils and macrophages with a fluorescent mesoionic acid fluoride

N. Kielland, M. Vendrell, R. Lavilla and Y. Chang, Chem. Commun., 2012, 48, 7401
DOI: 10.1039/C2CC32292G

Social activity

Search articles by author

Spotlight

Advertisements