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Issue 40, 2012
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Stereocontrolled access to optically-enriched oxabispidines

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Abstract

A range of chiral, optically-enriched bicyclic oxabispidines were prepared from (S)-(-)-2,3-epoxypropylphthalimide using an efficient sequence featuring a stereocontrolled intramolecular Mannich reaction as the key transformation.

Graphical abstract: Stereocontrolled access to optically-enriched oxabispidines

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Publication details

The article was received on 02 Feb 2012, accepted on 22 Mar 2012 and first published on 22 Mar 2012


Article type: Communication
DOI: 10.1039/C2CC30761H
Chem. Commun., 2012,48, 4836-4838

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    Stereocontrolled access to optically-enriched oxabispidines

    H. Brice, D. M. Gill, L. Goldie, P. S. Keegan, W. J. Kerr and P. H. Svensson, Chem. Commun., 2012, 48, 4836
    DOI: 10.1039/C2CC30761H

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