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Issue 23, 2012
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Synthesis and evaluation of triazole-linked poly(ε-caprolactone)-graft-poly(2-methyl-2-oxazoline) copolymers as potential drug carriers

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Abstract

Well-defined graft copolymers were obtained using a copper-catalysed azidealkyne Huisgen's cycloaddition click reaction from both biocompatible and non-toxic poly(ε-caprolactone) and poly(2-methyl-2-oxazoline) homopolymers. Resulting amphiphilic copolymers proved to form micelles that could be used as potential drug carriers.

Graphical abstract: Synthesis and evaluation of triazole-linked poly(ε-caprolactone)-graft-poly(2-methyl-2-oxazoline) copolymers as potential drug carriers

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Publication details

The article was received on 10 Jan 2012, accepted on 18 Jan 2012 and first published on 23 Jan 2012


Article type: Communication
DOI: 10.1039/C2CC30191A
Chem. Commun., 2012,48, 2879-2881

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    Synthesis and evaluation of triazole-linked poly(ε-caprolactone)-graft-poly(2-methyl-2-oxazoline) copolymers as potential drug carriers

    B. Guillerm, V. Darcos, V. Lapinte, S. Monge, J. Coudane and J. Robin, Chem. Commun., 2012, 48, 2879
    DOI: 10.1039/C2CC30191A

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