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Issue 17, 2012
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A Seoul-Fluor-based bioprobe for lipid droplets and its application in image-based high throughput screening

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Abstract

We developed a novel fluorescent bioprobe (SF44) that can specifically visualize the cellular lipid droplets in in vitro and in vivo systems and illustrated the mechanistic rationale of its fluorogenic property. Its application to image-based high throughput screening led us to the identification of a new small-molecule modulator of lipid droplet formation.

Graphical abstract: A Seoul-Fluor-based bioprobe for lipid droplets and its application in image-based high throughput screening

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Publication details

The article was received on 01 Dec 2011, accepted on 05 Jan 2012 and first published on 10 Jan 2012


Article type: Communication
DOI: 10.1039/C2CC17496K
Chem. Commun., 2012,48, 2331-2333

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    A Seoul-Fluor-based bioprobe for lipid droplets and its application in image-based high throughput screening

    E. Kim, S. Lee and S. B. Park, Chem. Commun., 2012, 48, 2331
    DOI: 10.1039/C2CC17496K

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