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Issue 21, 2012
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Iron-catalysed tandem cross-dehydrogenative coupling (CDC) of terminal allylic C(sp3) to C(sp2) of styrene and benzoannulation in the synthesis of polysubstituted naphthalenes

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Abstract

A novel iron-catalysed tandem cross-dehydrogenative coupling and benzoannulation process was developed for the synthesis of biologically and synthetically important polysubstituted naphthalene derivatives from simple 1,2-aryl-propenes and styrenes in moderate to good yields.

Graphical abstract: Iron-catalysed tandem cross-dehydrogenative coupling (CDC) of terminal allylic C(sp3) to C(sp2) of styrene and benzoannulation in the synthesis of polysubstituted naphthalenes

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Article information


Submitted
24 Nov 2011
Accepted
12 Jan 2012
First published
16 Jan 2012

Chem. Commun., 2012,48, 2674-2676
Article type
Communication

Iron-catalysed tandem cross-dehydrogenative coupling (CDC) of terminal allylic C(sp3) to C(sp2) of styrene and benzoannulation in the synthesis of polysubstituted naphthalenes

H. Liu, L. Cao, J. Sun, J. S. Fossey and W. Deng, Chem. Commun., 2012, 48, 2674
DOI: 10.1039/C2CC17330A

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