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Issue 2, 2013
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Bioinspired, releasable quorum sensing modulators

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We demonstrate the synthesis and immobilization of natural product hybrids featuring an acyl-homoserine lactone and a nitrodopamine onto biocompatible TiO2 surfaces through an operationally simple dip-and-rinse procedure. The resulting immobilized hybrids were shown to be powerful quorum sensing (QS) activators in Pseudomonas strains acting by slow release from the surface.

Graphical abstract: Bioinspired, releasable quorum sensing modulators

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The article was received on 05 Oct 2012, accepted on 02 Nov 2012 and first published on 02 Nov 2012

Article type: Communication
DOI: 10.1039/C2CC37287H
Chem. Commun., 2013,49, 155-157

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    Bioinspired, releasable quorum sensing modulators

    J. Gomes, A. Grunau, A. K. Lawrence, L. Eberl and K. Gademann, Chem. Commun., 2013, 49, 155
    DOI: 10.1039/C2CC37287H

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