Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 70, 2012
Previous Article Next Article

A target-activated autocatalytic DNAzyme amplification strategy for the assay of base excision repair enzyme activity

Author affiliations

Abstract

Based on a target-activated autocatalytic DNAzyme amplification strategy, novel fluorescence sensing platforms were constructed for highly sensitive and selective assay of base excision repair enzyme activity. By using a rolling circle amplification (RCA)-coupled amplification cascade, an extremely low detection limit (0.002 U mL−1) was achieved.

Graphical abstract: A target-activated autocatalytic DNAzyme amplification strategy for the assay of base excision repair enzyme activity

Back to tab navigation

Supplementary files

Article information


Submitted
25 Jun 2012
Accepted
16 Jul 2012
First published
17 Jul 2012

Chem. Commun., 2012,48, 8820-8822
Article type
Communication

A target-activated autocatalytic DNAzyme amplification strategy for the assay of base excision repair enzyme activity

L. Zhang, J. Zhao, J. Jiang and R. Yu, Chem. Commun., 2012, 48, 8820
DOI: 10.1039/C2CC34531E

Social activity

Search articles by author

Spotlight

Advertisements