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Issue 63, 2012
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Radiolabeled γ-AApeptides: a new class of tracers for positron emission tomography

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Abstract

A γ-AApeptide-based tracer for positron emission tomography imaging of integrin αvβ3 is reported. Despite its shorter sequence and linear nature, this tracer had comparable integrin αvβ3 binding affinity to the cyclic arginine-glycine-aspartic acid peptide but significantly higher resistance to enzymatic degradation and better stability.

Graphical abstract: Radiolabeled γ-AApeptides: a new class of tracers for positron emission tomography

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Supplementary files

Article information


Submitted
07 Mar 2012
Accepted
10 Jun 2012
First published
19 Jun 2012

Chem. Commun., 2012,48, 7850-7852
Article type
Communication

Radiolabeled γ-AApeptides: a new class of tracers for positron emission tomography

Y. Yang, Y. Niu, H. Hong, H. Wu, Y. Zhang, J. W. Engle, T. E. Barnhart, J. Cai and W. Cai, Chem. Commun., 2012, 48, 7850
DOI: 10.1039/C2CC33620K

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