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Issue 10, 2012
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Sulfo-click reaction via in situ generated thioacids and its application in kinetic target-guided synthesis

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Abstract

Herein, we describe a practical, one-pot variant of the sulfo-click reaction, in which 9-fluorenylmethyl-protected thioesters are rapidly deprotected and reacted further with sulfonylazides to give N-acyl sulfonamides.

Graphical abstract: Sulfo-click reaction via in situ generated thioacids and its application in kinetic target-guided synthesis

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Supplementary files

Article information


Submitted
31 Jul 2011
Accepted
15 Aug 2011
First published
05 Sep 2011

Chem. Commun., 2012,48, 1526-1528
Article type
Communication

Sulfo-click reaction via in situ generated thioacids and its application in kinetic target-guided synthesis

N. K. Namelikonda and R. Manetsch, Chem. Commun., 2012, 48, 1526
DOI: 10.1039/C1CC14724B

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