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Issue 19, 2012
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Gold nanoparticles-based nanoconjugates for enhanced enzyme cascade and glucose sensing

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Abstract

We have coupled gold nanoparticles with horseradish peroxidase (HRP) to assemble catalytic nanoconjugates (HRP-AuNPs) for glucose detection. We found that a proper mixing ratio of HRP/AuNPs can significantly improve catalytic activity for the cascade reaction, an effect arising from increased spatial coupling between enzymes. Such gold nanoparticle-based nanoconjugates are shown to be promising nanosensors for glucose.

Graphical abstract: Gold nanoparticles-based nanoconjugates for enhanced enzyme cascade and glucose sensing

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Publication details

The article was received on 03 Jul 2012, accepted on 07 Aug 2012 and first published on 09 Aug 2012


Article type: Paper
DOI: 10.1039/C2AN35900F
Analyst, 2012,137, 4435-4439

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    Gold nanoparticles-based nanoconjugates for enhanced enzyme cascade and glucose sensing

    D. Zeng, W. Luo, J. Li, H. Liu, H. Ma, Q. Huang and C. Fan, Analyst, 2012, 137, 4435
    DOI: 10.1039/C2AN35900F

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