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Issue 23, 2012
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Fluorescent polymer-based post-translational differentiation and subtyping of breast cancer cells

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Abstract

Herein, we report the application of synthesized fluorescent, water soluble polymers for post-translational subtyping and differentiation of breast cancer cells in vitro. The fluorescence emission spectra from these polymers were modulated differently in the presence of conditioned cell culture media from various breast cancer cells. These polymers differentiate at a post-translation level possibly due to their ability to interact with extracellular enzymes that are over-expressed in cancerous conditions.

Graphical abstract: Fluorescent polymer-based post-translational differentiation and subtyping of breast cancer cells

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Publication details

The article was received on 27 Jun 2012, accepted on 03 Oct 2012 and first published on 04 Oct 2012


Article type: Communication
DOI: 10.1039/C2AN35877H
Analyst, 2012,137, 5487-5490

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    Fluorescent polymer-based post-translational differentiation and subtyping of breast cancer cells

    M. D. Scott, R. Dutta, M. K. Haldar, A. Wagh, T. R. Gustad, B. Law, D. L. Friesner and S. Mallik, Analyst, 2012, 137, 5487
    DOI: 10.1039/C2AN35877H

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