pH-responsive, dynamically restructuring hydrogels formed by reversible crosslinking of PVA with phenylboronic acid functionalised PPO–PEO–PPO spacers (Jeffamines®)
Abstract
Dynamically restructuring (“self-healing”) hydrogels were prepared by reversible formation of boronic-ester crosslinks between α,ω-phenylboronic acid terminated PPO–PEO–PPO spacers and poly(vinyl alcohol) (PVA). For this purpose two different bis-(phenylboronic acid) functionalised crosslinkers with Jeff–2AMPBA and Jeff–4AMPBA were synthesised via reductive coupling of 2- and