Synthesis of human GLP-1 (7–36) by chemoselective α-ketoacid–hydroxylaminepeptide ligation of unprotected fragments†
Abstract
The synthesis of the bioactive form of human glucagon-like
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* Corresponding authors
a Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, USA
b IPSEN/Biomeasure, Inc., 27 Maple Street, Milford, MA, USA
c
Laboratorium für Organische Chemie, ETH–Zürich, Zürich, Switzerland
E-mail:
bode@org.chem.ethz.ch
Tel: +41 44 633 21 03
The synthesis of the bioactive form of human glucagon-like
J. Wu, J. Ruiz-Rodríguez, J. M. Comstock, J. Z. Dong and J. W. Bode, Chem. Sci., 2011, 2, 1976 DOI: 10.1039/C1SC00398D
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