Issue 4, 2011
From the journal:

RSC Advances

Solid phase synthesis of ultra-photostable cyanine NIR dye library†

Raj Kumar Das,a   Animesh Samanta,a   Hyung-Ho Hab  and  Young-Tae Chang*ac  

* Corresponding authors

a Department of Chemistry & MedChem Program of Life Sciences Institute, National University of Singapore, Singapore
E-mail: chmcyt@nus.edu.sg
Fax: +65-6779-1691
Tel: +65-6516-7794

b College of Pharmacy, Sunchon National University, South Korea

c Laboratory of Bioimaging Probe Development, Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #02-02 Helios Building, Singapore

Abstract

Photostability is one of the key issues in NIR dyes and we have previously reported a photostable CyNA library. Herein we report an ultra-photostable cyanine-based NIR fluorescence library, CyR, utilizing the stability component of CyNA. Efficient solid phase chemistry was also devised to provide a robust synthetic route to the new library.

Graphical abstract: Solid phase synthesis of ultra-photostable cyanine NIR dye library

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Article information

DOI
https://doi.org/10.1039/C1RA00498K
Article type
Communication
Submitted
21 Jul 2011
Accepted
21 Jul 2011
First published
24 Aug 2011

RSC Adv., 2011,1, 573-575

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Solid phase synthesis of ultra-photostable cyanine NIR dye library

R. K. Das, A. Samanta, H. Ha and Y. Chang, RSC Adv., 2011, 1, 573 DOI: 10.1039/C1RA00498K

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