Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 4, 2011
Previous Article Next Article

Poly(N-isopropylacrylamide) branched polymernanoparticles

Author affiliations

Abstract

A series of thermally responsive branched copolymers based on N-isopropylacrylamide (NIPAAm) and poly(ethylene glycol) methacrylate (PEGMA) are synthesized using a direct, single step modified free radical polymerization strategy. The aqueous solution behaviour and nanoparticle formation of these copolymers are studied and correlated to the NIPAAm : PEGMA molar ratio and PEGMA chain length. All copolymers are water-soluble as discrete polymer chains at low temperature. On raising the solution temperature, inter-polymer interactions—that is, aggregation of polymers—are inhibited at higher PEGMA molar ratios and at long PEGMA chain lengths. The statistical incorporation of monomer residues and the short primary chain lengths within these branched copolymer structures result in the effective “dampening out” of NIPAAm thermo-responsivity and provides new insight into the architecture and composition of these complex copolymer structures.

Graphical abstract: Poly(N-isopropylacrylamide) branched polymer nanoparticles

Back to tab navigation

Article information


Submitted
10 Nov 2010
Accepted
21 Dec 2010
First published
24 Jan 2011

Polym. Chem., 2011,2, 941-949
Article type
Paper

Poly(N-isopropylacrylamide) branched polymer nanoparticles

P. Chambon, L. Chen, S. Furzeland, D. Atkins, J. V. M. Weaver and D. J. Adams, Polym. Chem., 2011, 2, 941
DOI: 10.1039/C0PY00369G

Social activity

Search articles by author

Spotlight

Advertisements