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Issue 3, 2011

Tunable thermo-responsive polymer–protein conjugates via a combination of nucleophilic thiol–ene “click” and SET-LRP

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Abstract

Herein we report the synthesis of a protein macroinitiator in a one-pot strategy using phosphine-mediated thiol–ene “click”, the macroinitiator was used to polymerise ethylene glycol containing monomers to yield polymerprotein conjugates with tunable thermoresponsive behaviour.

Graphical abstract: Tunable thermo-responsive polymer–protein conjugates via a combination of nucleophilic thiol–ene “click” and SET-LRP

Supplementary files

Article information


Submitted
03 Oct 2010
Accepted
24 Oct 2010
First published
09 Nov 2010

Polym. Chem., 2011,2, 572-574
Article type
Communication

Tunable thermo-responsive polymerprotein conjugates via a combination of nucleophilic thiol–ene “click” and SET-LRP

M. W. Jones, M. I. Gibson, G. Mantovani and D. M. Haddleton, Polym. Chem., 2011, 2, 572 DOI: 10.1039/C0PY00329H

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