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Issue 15, 2011
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A naphthalene-based Al3+ selective fluorescent sensor for living cell imaging

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Abstract

An efficient fluorescent Al3+ receptor, N-(2-hydroxy-1-naphthalene)-N′-(2-(2-hydroxy-1-naphthalene)amino-ethyl)-ethane-1,2-diamine (L) has been synthesized by the condensation reaction between 2-hydroxy naphthaldehyde and diethylenetriamine. High selectivity and affinity of L towards Al3+ in ethanol (EtOH) as well as in HEPES buffer at pH 7.4, makes it suitable to detect intracellular Al3+ with fluorescence microscopy. Metal ions, viz.Li+, Na+, K+, Mg2+, Ca2+, Mn2+, Co2+, Ni2+, Cu2+, Zn2+, Ag+, Cd2+, Hg2+ and Pb2+ do not interfere. The lowest detection limit for Al3+ is 3.0 × 10−7 M and 1.0 × 10−7 M in EtOH and HEPES buffer respectively.

Graphical abstract: A naphthalene-based Al3+ selective fluorescent sensor for living cell imaging

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Supplementary files

Article information


Submitted
26 Mar 2011
Accepted
10 May 2011
First published
21 Jun 2011

Org. Biomol. Chem., 2011,9, 5523-5529
Article type
Paper

A naphthalene-based Al3+ selective fluorescent sensor for living cell imaging

A. Sahana, A. Banerjee, S. Das, S. Lohar, D. Karak, B. Sarkar, S. Kanti Mukhopadhyay, A. K. Mukherjee and D. Das, Org. Biomol. Chem., 2011, 9, 5523
DOI: 10.1039/C1OB05479A

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