Jump to main content
Jump to site search

Issue 14, 2011
Previous Article Next Article

Phosphine-catalyzed [3 + 2] cycloaddition of allenoates with trifluoromethylketones: synthesis of dihydrofurans and tetrahydrofurans

Author affiliations

Abstract

The triphenylphosphine-catalyzed formal [3 + 2] cycloaddition of allenoates and trifluoromethylketones was realized to give the corresponding dihydrofurans in good yields with excellent γ-regioselectivities. Hydrogenation of the dihydrofurans gave 2,4,4-trisubstituted tetrahydrofurans in good yields with exclusive cis-selectivities.

Graphical abstract: Phosphine-catalyzed [3 + 2] cycloaddition of allenoates with trifluoromethylketones: synthesis of dihydrofurans and tetrahydrofurans

Back to tab navigation

Supplementary files

Article information


Submitted
21 Mar 2011
Accepted
21 Apr 2011
First published
05 May 2011

Org. Biomol. Chem., 2011,9, 5260-5265
Article type
Paper

Phosphine-catalyzed [3 + 2] cycloaddition of allenoates with trifluoromethylketones: synthesis of dihydrofurans and tetrahydrofurans

T. Wang and S. Ye, Org. Biomol. Chem., 2011, 9, 5260
DOI: 10.1039/C1OB05444A

Social activity

Search articles by author

Spotlight

Advertisements