Issue 13, 2011
From the journal:

Organic & Biomolecular Chemistry

The clerodane ring system: investigating the viability of a direct Diels–Alder approach†

Andrew T. Merritt,a   Rebecca H. Pouwer,b   David J. Williams,c   Craig M. Williams*b  and  Steven V. Ley*d  

* Corresponding authors

a Medical Research Council Technology, 1–3 Burtonhole Lane, Mill Hill, London, UK

b School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia
E-mail: c.williams3@uq.edu.au

c Chemical Crystallography Laboratory, Department of Chemistry, Imperial College London, South Kensington, London, UK

d Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK
E-mail: svl1000@cam.ac.uk

Abstract

A direct synthetic approach to the spiro-γ-lactone clerodane ring system has been investigated. This work builds on that of Jung and highlights the inherent difficulties associated with the otherwise obvious Diels–Alder approach.

Graphical abstract: The clerodane ring system: investigating the viability of a direct Diels–Alder approach

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Article information

DOI
https://doi.org/10.1039/C1OB05422H
Article type
Communication
Submitted
17 Mar 2011
Accepted
27 Apr 2011
First published
19 May 2011

Org. Biomol. Chem., 2011,9, 4745-4747

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The clerodane ring system: investigating the viability of a direct Diels–Alder approach

A. T. Merritt, R. H. Pouwer, D. J. Williams, C. M. Williams and S. V. Ley, Org. Biomol. Chem., 2011, 9, 4745 DOI: 10.1039/C1OB05422H

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