Groebke multicomponent reaction and subsequent nucleophilic aromatic substitution for a convenient synthesis of 3,8-diaminoimidazo[1,2-a]pyrazines as potential kinase inhibitors†
Abstract
In a program aimed at discovering novel
* Corresponding authors
a
DiSCAFF, Università degli Studi del Piemonte Orientale, via Bovio 6, Novara, Italy
E-mail:
tracey.pirali@pharm.unipmn.it
Fax: (+39)0321375821
Tel: (+39)0321375853
b Molecular Biotechnology Center, Università degli Studi di Torino, Torino, Italy
c Department of Biological Science and Bioengineering, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China
In a program aimed at discovering novel
M. Guasconi, X. Lu, A. Massarotti, A. Caldarelli, E. Ciraolo, G. C. Tron, E. Hirsch, G. Sorba and T. Pirali, Org. Biomol. Chem., 2011, 9, 4144 DOI: 10.1039/C1OB05336A
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