Issue 7, 2011
From the journal:

Organic & Biomolecular Chemistry

An environmentally friendly Mukaiyama aldol reaction catalyzed by a strong Brønsted acid in solvent-free conditions†

Margherita Barbero,*a   Stefano Bazzi,a   Silvano Cadamuro,a   Stefano Dughera,a   Claudio Magistris,a   Alessandra Smarraa  and  Paolo Venturelloa  

* Corresponding authors

a Dipartimento di Chimica Generale e Chimica Organica, Università degli Studi di Torino, Via Pietro Giuria, 7, Torino, Italy
E-mail: margherita.barbero@unito.it
Fax: +390116707642
Tel: +390116707645

Abstract

o-Benzenedisulfonimide, a new strong bench-stable Brønsted acid, has been shown to efficiently catalyze the Mukaiyama aldol reaction of aldehydes or dimethyl acetals with silyl enol ethers under mild solvent-free reaction conditions.

Graphical abstract: An environmentally friendly Mukaiyama aldol reaction catalyzed by a strong Brønsted acid in solvent-free conditions

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Article information

DOI
https://doi.org/10.1039/C0OB00837K
Article type
Paper
Submitted
06 Oct 2010
Accepted
16 Dec 2010
First published
07 Feb 2011

Org. Biomol. Chem., 2011,9, 2192-2197

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An environmentally friendly Mukaiyama aldol reaction catalyzed by a strong Brønsted acid in solvent-free conditions

M. Barbero, S. Bazzi, S. Cadamuro, S. Dughera, C. Magistris, A. Smarra and P. Venturello, Org. Biomol. Chem., 2011, 9, 2192 DOI: 10.1039/C0OB00837K

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