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Issue 1, 2011
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First total synthesis of antrocamphin A and its analogs as anti-inflammatory and anti-platelet aggregation agents

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Abstract

Naturally occurring antrocamphin A (1) is a potent anti-inflammatory compound from the edible fungus Antrodia camphorata (Taiwanofungus camphoratus), whose wild fruiting body is used as a valuable folk medicine in Taiwan. This study is the first total synthesis of antrocamphin A (1) and its analogs. Their inhibition ability on NO release, superoxide anion generation, elastase release and platelet aggregation are reported herein.

Graphical abstract: First total synthesis of antrocamphin A and its analogs as anti-inflammatory and anti-platelet aggregation agents

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Article information


Submitted
23 Aug 2010
Accepted
01 Nov 2010
First published
18 Nov 2010

Org. Biomol. Chem., 2011,9, 70-73
Article type
Communication

First total synthesis of antrocamphin A and its analogs as anti-inflammatory and anti-platelet aggregation agents

C. Lee, C. Huang, H. Wang, D. Chuang, M. Wu, S. Wang, T. Hwang, C. Wu, Y. Chen, F. Chang and Y. Wu, Org. Biomol. Chem., 2011, 9, 70
DOI: 10.1039/C0OB00616E

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