Issue 10, 2011
From the journal:

Nanoscale

Multifunctional nanoadditives for the thermodynamic and kinetic stabilization of enzymes†

Tristan D. Clemons,ab   Cameron W. Evans,ab   Bogdan Zdyrko,c   Igor Luzinov,c   Melinda Fitzgerald,b   Sarah A. Dunlop,b   Alan R. Harvey,d   K. Swaminathan Iyer*a  and  Keith A. Stubbs*a  

* Corresponding authors

a School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA, Australia
E-mail: keith.stubbs@uwa.edu.au, swaminatha.iyer@uwa.edu.au
Tel: +61 6488-2725

b Experimental and Regenerative Neurosciences, School of Animal Biology, The University of Western Australia, Crawley, WA, Australia

c School of Materials Science and Engineering, Clemson University, Clemson, SC, USA

d School of Anatomy and Human Biology, The University of Western Australia, Crawley, WA, Australia

Abstract

Stabilization of enzymes has become a major focus in the quest to improve the activity, sustainability and recyclability of enzymes for their successful integration into both industry and medicine. Here, we describe the kinetic and thermodynamic stabilization of a variety of enzymes in the presence of cationic multifunctional polymeric nanoparticles.

Graphical abstract: Multifunctional nanoadditives for the thermodynamic and kinetic stabilization of enzymes

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Article information

DOI
https://doi.org/10.1039/C1NR10786K
Article type
Communication
Submitted
11 Jul 2011
Accepted
12 Aug 2011
First published
06 Sep 2011

Nanoscale, 2011,3, 4085-4087

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Multifunctional nanoadditives for the thermodynamic and kinetic stabilization of enzymes

T. D. Clemons, C. W. Evans, B. Zdyrko, I. Luzinov, M. Fitzgerald, S. A. Dunlop, A. R. Harvey, K. S. Iyer and K. A. Stubbs, Nanoscale, 2011, 3, 4085 DOI: 10.1039/C1NR10786K

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