Issue 4, 2011
From the journal:

Natural Product Reports

Natural withanolides: an overview

Li-Xia Chen,a   Hao Hea  and  Feng Qiu*a  

* Corresponding authors

a Department of Natural Products Chemistry, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, No. 103 Road Wenhua, Shenyang, PR China
E-mail: fengqiu2000@tom.com
Fax: +86 24-23993994
Tel: +86 24-23986463

Abstract

Covering: August 1996 to March 2010

Withanolides are a group of naturally occurring C28 steroids built on an ergostane skeleton functionalized at carbons 1, 22 and 26, commonly known as the withanolide skeleton. Over the period of August 1996 to March 2010, 360 new naturally occurring withanolides were isolated and identified. This review provides a comprehensive summary of the structural classification and distribution of these new compounds. The diverse biological and pharmacological activities of natural withanolides are also discussed based on their structural features. A total of 211 references are cited in this review.

Graphical abstract: Natural withanolides: an overview

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Article information

DOI
https://doi.org/10.1039/C0NP00045K
Article type
Review Article
Submitted
20 Sep 2010
First published
23 Feb 2011

Nat. Prod. Rep., 2011,28, 705-740

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Natural withanolides: an overview

L. Chen, H. He and F. Qiu, Nat. Prod. Rep., 2011, 28, 705 DOI: 10.1039/C0NP00045K

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