Issue 12, 2011

Minisci reactions: Versatile CH-functionalizations for medicinal chemists

Abstract

The addition of a radical to a heteroaromatic base is commonly referred to as a Minsici reaction. Such reactions constitute a broad-set of selective CH-functionalization processes. This review describes some of the major applications of Minisci reactions and related processes to medicinal or biological chemistry, and highlights some potential developments within this area.

Graphical abstract: Minisci reactions: Versatile CH-functionalizations for medicinal chemists

Article information

Article type
Review Article
Submitted
24 May 2011
Accepted
03 Jul 2011
First published
22 Aug 2011

Med. Chem. Commun., 2011,2, 1135-1161

Minisci reactions: Versatile CH-functionalizations for medicinal chemists

M. A. J. Duncton, Med. Chem. Commun., 2011, 2, 1135 DOI: 10.1039/C1MD00134E

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