Air stream-mediated vortex agitation of microlitre entities on a fluidic chip

Abstract

The method presented in this paper uses air flux to induce spiral motion in small-scale (e.g., microlitre) fluid entities in an efficient, technologically convenient manner. The set-up entails a manifold that modulates the air flux and projects it onto a liquid-containing reservoir. The flow behaviour of the liquid phase has been visualized through the dissolution of rhodamine B crystallites and the motion of fluorescent microbeads. In addition, the method proved effective to restoring a suspension of spherical particles upon sedimentation, promoting displacement and capture of the beads within a microfluidic system.