Issue 9, 2011
From the journal:

Green Chemistry

O-Alkylation of phenol derivatives via a nucleophilic substitution

Clément Cazorla,a   Émilie Pfordt,a   Marie-Christine Duclos,a   Estelle Métaya  and  Marc Lemaire*a  

* Corresponding authors

a Laboratoire de CAtalyse SYnthèse et ENvironnement, Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (ICBMS), CNRS, UMR5246, Université Lyon 1, 43 Boulevard du 11 Novembre 1918, Bat CPE, Villeurbanne, France
E-mail: marc.lemaire@univ-lyon1.fr
Fax: +33-472-43-14-08
Tel: +33-472-43-14-07

Abstract

The alkylation of phenol derivatives can be achieved in good yield via Lewis or Brønsted acid. The only by-product of the reaction is water and the catalyst can be recycled when using Brønsted acid.

Graphical abstract: O-Alkylation of phenol derivatives via a nucleophilic substitution

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Article information

DOI
https://doi.org/10.1039/C1GC15481H
Article type
Paper
Submitted
29 Apr 2011
Accepted
16 Jun 2011
First published
18 Jul 2011

Green Chem., 2011,13, 2482-2488

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O-Alkylation of phenol derivatives via a nucleophilic substitution

C. Cazorla, É. Pfordt, M. Duclos, E. Métay and M. Lemaire, Green Chem., 2011, 13, 2482 DOI: 10.1039/C1GC15481H

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