Jump to main content
Jump to site search

Issue 10, 2011
Previous Article Next Article

Pyrazolin-4-ylidenes: a new class of intriguing ligands

Author affiliations


The immense success of N-heterocyclic carbenes in recent years has initiated the search for even stronger ligands leading to the discovery of abnormal and remote NHCs. This article reflects our particular interest in the coordination chemistry of pyrazolin-4-ylidenes as a contribution to this field. A modular approach to 4-iodopyrazolium salts with different substitution patterns is described, which upon oxidative addition to Pd0 gave rise to a library of new Pd(II) pyrazolin-4-ylidene complexes. A preliminary study showed that selected complexes are active precatalysts in Suzuki–Miyaura and Mizoroki–Heck coupling reactions. The 3,5-substituents of pyrazolin-4-ylidenes are found to have significant effects on complexation and catalytic activities. Finally, the nature of this new class of ligands is discussed, and a future direction for further explorations in this exciting field is envisioned.

Graphical abstract: Pyrazolin-4-ylidenes: a new class of intriguing ligands

Back to tab navigation

Publication details

The article was received on 17 Aug 2010, accepted on 22 Oct 2010 and first published on 06 Dec 2010

Article type: Perspective
DOI: 10.1039/C0DT01037E
Dalton Trans., 2011,40, 2141-2147

  •   Request permissions

    Pyrazolin-4-ylidenes: a new class of intriguing ligands

    Y. Han and H. V. Huynh, Dalton Trans., 2011, 40, 2141
    DOI: 10.1039/C0DT01037E

Search articles by author