Issue 9, 2011
From the journal:

Chemical Society Reviews

Bioconjugation viaazide–Staudinger ligation: an overview

Christine I. Schilling,a   Nicole Jung,ab   Moritz Biskup,a   Ute Schepers*c  and  Stefan Bräse*a  

* Corresponding authors

a Institute of Organic Chemistry, Karlsruhe Institute of Technology, Fritz-Haber-Weg 6, D-76131 Karlsruhe, Germany
E-mail: braese@kit.edu
Fax: +49 (0)721 608 48581
Tel: +49 (0)721 608 42903

b KIT Combinatorial Platform, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz, D-76344 Eggenstein-Leopoldshafen, Germany

c Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz, D-76344 Eggenstein-Leopoldshafen, Germany
E-mail: ute.schepers@kit.edu
Fax: +49 (0)721 608 23354
Tel: +49 (0)7247 82 3444

Abstract

Bioconjugation techniques using organic azides are compared in this critical review. A particular focus is on chemical ligation reactions and their application to chemical biology (179 references).

Graphical abstract: Bioconjugation viaazide–Staudinger ligation: an overview

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Article information

DOI
https://doi.org/10.1039/C0CS00123F
Article type
Critical Review
Submitted
25 Sep 2010
First published
17 Jun 2011

Chem. Soc. Rev., 2011,40, 4840-4871

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Bioconjugation viaazide–Staudinger ligation: an overview

C. I. Schilling, N. Jung, M. Biskup, U. Schepers and S. Bräse, Chem. Soc. Rev., 2011, 40, 4840 DOI: 10.1039/C0CS00123F

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