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Issue 8, 2011
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Monoolein: a magic lipid?

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Abstract

During the last few years, there has been an extraordinary increase in publications describing the manifold applications of monoolein, one of the most important lipids in the fields of drug delivery, emulsion stabilization and protein crystallization. In this perspective we present a comprehensive review of the phase behavior of this ‘magic lipid’. An account of various mesophases formed in the presence of water and a collection of formulae for the calculation of their nano-structural parameters are provided. Effects of chemical and biological molecules including lipids, detergents, salts, sugars, proteins and DNA on the classical behavior are also discussed. Physicochemical triggers such as, temperature, pressure and shearing modulate the phase behavior of monoolein self assemblies that are covered in subsequent sections. Finally the growing applications of monoolein in various fields are also reported.

Graphical abstract: Monoolein: a magic lipid?

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Article information


Submitted
18 Aug 2010
Accepted
08 Nov 2010
First published
23 Dec 2010

Phys. Chem. Chem. Phys., 2011,13, 3004-3021
Article type
Perspective

Monoolein: a magic lipid?

C. V. Kulkarni, W. Wachter, G. Iglesias-Salto, S. Engelskirchen and S. Ahualli, Phys. Chem. Chem. Phys., 2011, 13, 3004 DOI: 10.1039/C0CP01539C

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