Issue 46, 2011

Wash-free magnetic oligonucleotide probes-based NMR sensor for detecting the Hg ion

Abstract

An easily applied and sensitive sensor for the detection of heavy metal ion residues based entirely on magnetic nanoparticle and oligonucleotide was developed. The tool is established on the relaxation of magnetic nanoparticles with different dispersion states. The target analyte, Hg ions, induce the aggregation of the MNP oligonucleotide probes. Accordingly, the light produced by the magnetic relaxation image and the transverse relaxation time (T2) all change due to the effect of the aggregation. The limit of qualitative detection of the sensor is 0.15 ppt. The recoveries from test samples range between 97.1–101.8%. Using the nuclear resonance instrument, the method is a high throughput and sensitive sensor.

Graphical abstract: Wash-free magnetic oligonucleotide probes-based NMR sensor for detecting the Hg ion

Supplementary files

Article information

Article type
Communication
Submitted
26 Sep 2011
Accepted
07 Oct 2011
First published
25 Oct 2011

Chem. Commun., 2011,47, 12503-12505

Wash-free magnetic oligonucleotide probes-based NMR sensor for detecting the Hg ion

W. Ma, C. Hao, W. Ma, C. Xing, W. Yan, H. Kuang, L. Wang and C. Xu, Chem. Commun., 2011, 47, 12503 DOI: 10.1039/C1CC15967D

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