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Issue 48, 2011
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Solid-phase synthesis of arginine-based double-tailed cationic lipopeptides: potent nucleic acid carriers

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Abstract

Herein we report a highly-efficient solid-phase strategy for the modular synthesis of 63 double-tailed lipid-peptide conjugates and their application in DNA delivery.

Graphical abstract: Solid-phase synthesis of arginine-based double-tailed cationic lipopeptides: potent nucleic acid carriers

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Supplementary files

Article information


Submitted
19 Sep 2011
Accepted
14 Oct 2011
First published
01 Nov 2011

Chem. Commun., 2011,47, 12774-12776
Article type
Communication

Solid-phase synthesis of arginine-based double-tailed cationic lipopeptides: potent nucleic acid carriers

A. Liberska, A. Lilienkampf, A. Unciti-Broceta and M. Bradley, Chem. Commun., 2011, 47, 12774
DOI: 10.1039/C1CC15805H

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