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Issue 44, 2011
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Asymmetric reduction of ketones with recombinant E. coli whole cells in neat substrates

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Abstract

The asymmetric reduction of ketones is performed by using lyophilized whole cells in neat substrates with defined water activity (aw). Ketones and alcohols prone to be unstable in aqueous media can now be converted via biocatalysis.

Graphical abstract: Asymmetric reduction of ketones with recombinant E. coli whole cells in neat substrates

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Article information


Submitted
08 Jul 2011
Accepted
05 Oct 2011
First published
17 Oct 2011

Chem. Commun., 2011,47, 12230-12232
Article type
Communication

Asymmetric reduction of ketones with recombinant E. coli whole cells in neat substrates

A. Jakoblinnert, R. Mladenov, A. Paul, F. Sibilla, U. Schwaneberg, M. B. Ansorge-Schumacher and P. D. de María, Chem. Commun., 2011, 47, 12230
DOI: 10.1039/C1CC14097C

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