Issue 28, 2011
From the journal:

Chemical Communications

Tandem indole C–H alkenylation/arylation for tetra-substituted alkene synthesis†

Laura Lopez Suareza  and  Michael F. Greaney*a  

* Corresponding authors

a School of Chemistry, University of Edinburgh, King's Buildings, West Mains Rd, Edinburgh, UK
E-mail: Michael.Greaney@ed.ac.uk

Abstract

Alkynyl indoles undergo a novel sequence of Pd-catalysed indole C–H activation/alkyne carbopalladation/arylation, with diaryliodonium salts providing the aryl components. An array of functionalised indole alkenes have been prepared in good to excellent yield, with the reaction being selective for the Z-alkene.

Graphical abstract: Tandem indole C–H alkenylation/arylation for tetra-substituted alkene synthesis

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1CC13094C
Article type
Communication
Submitted
26 May 2011
Accepted
03 Jun 2011
First published
20 Jun 2011

Chem. Commun., 2011,47, 7992-7994

Permissions

Request permissions

Tandem indole C–H alkenylation/arylation for tetra-substituted alkene synthesis

L. L. Suarez and M. F. Greaney, Chem. Commun., 2011, 47, 7992 DOI: 10.1039/C1CC13094C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements