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Issue 29, 2011
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Highly diastereo- and enantioselective one-pot Michael–Aldol reactions of α,β-unsaturated aldehydes with imidazole derivatives

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Abstract

Highly diastereo- and enantioselective one-pot Michael–Aldol reactions of α,β-unsaturated aldehydes with imidazole derivatives have been developed. The cascade reactions products could be obtained with three stereocenters in high yields and excellent diastereo- and enantioselectivities.

Graphical abstract: Highly diastereo- and enantioselective one-pot Michael–Aldol reactions of α,β-unsaturated aldehydes with imidazole derivatives

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Publication details

The article was received on 20 Apr 2011, accepted on 02 Jun 2011 and first published on 20 Jun 2011


Article type: Communication
DOI: 10.1039/C1CC12300A
Chem. Commun., 2011,47, 8325-8327

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    Highly diastereo- and enantioselective one-pot Michael–Aldol reactions of α,β-unsaturated aldehydes with imidazole derivatives

    W. Li, X. Li, W. Wu, X. Liang and J. Ye, Chem. Commun., 2011, 47, 8325
    DOI: 10.1039/C1CC12300A

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