Issue 18, 2011
From the journal:

Chemical Communications

Signal amplification of streptavidin–horseradish peroxidase functionalized carbon nanotubes for amperometric detection of attomolar DNA†

Wenchao Gao,a   Haifeng Dong,a   Jianping Lei,*a   Hanxu Jia  and  Huangxian Ju*a  

* Corresponding authors

a Key Laboratory of Analytical Chemistry for Life Science (Ministry of Education of China), Department of Chemistry, Nanjing University, Nanjing 210093, P.R. China
E-mail: hxju@nju.edu.cn, jpl@nju.edu.cn
Fax: +86 25 83593593
Tel: +86 25 83593593

Abstract

A novel biosensing strategy for selective electrochemical detection of DNA down to the attomolar level with a linear range of 5 orders of magnitude was developed by the specific recognitions of target DNA and streptavidin to biotin labelled molecular beacon and signal amplification of streptavidin–horseradish peroxidase functionalized carbon nanotubes.

Graphical abstract: Signal amplification of streptavidin–horseradish peroxidase functionalized carbon nanotubes for amperometric detection of attomolar DNA

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Article information

DOI
https://doi.org/10.1039/C1CC10840A
Article type
Communication
Submitted
14 Feb 2011
Accepted
08 Mar 2011
First published
02 Apr 2011

Chem. Commun., 2011,47, 5220-5222

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Signal amplification of streptavidin–horseradish peroxidase functionalized carbon nanotubes for amperometric detection of attomolar DNA

W. Gao, H. Dong, J. Lei, H. Ji and H. Ju, Chem. Commun., 2011, 47, 5220 DOI: 10.1039/C1CC10840A

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