Issue 15, 2011
From the journal:

Chemical Communications

Catalytic asymmetric syntheses of isoxazoline-N-oxides under phase-transfer conditions†

Taichi Kano,a   Akihiro Yamamoto,a   Sunhwa Songa  and  Keiji Maruoka*a  

* Corresponding authors

a Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan
E-mail: maruoka@kuchem.kyoto-u.ac.jp
Fax: +81 75-753-4041
Tel: +81 75-753-4041

Abstract

Catalytic asymmetric syntheses of various isoxazoline-N-oxides have been accomplished by asymmetric phase-transfer conjugate addition of bromomalonate to nitroolefins and subsequent ring-closing O-alkylation.

Graphical abstract: Catalytic asymmetric syntheses of isoxazoline-N-oxides under phase-transfer conditions

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Article information

DOI
https://doi.org/10.1039/C0CC05786J
Article type
Communication
Submitted
25 Dec 2010
Accepted
13 Jan 2011
First published
01 Feb 2011

Chem. Commun., 2011,47, 4358-4360

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Catalytic asymmetric syntheses of isoxazoline-N-oxides under phase-transfer conditions

T. Kano, A. Yamamoto, S. Song and K. Maruoka, Chem. Commun., 2011, 47, 4358 DOI: 10.1039/C0CC05786J

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