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Issue 4, 2011
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The functional valency of dodecamannosylated fullerenes with Escherichia coli FimH—towards novel bacterial antiadhesives

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Abstract

Fullerene hexakis-adducts bearing 12 peripheral mannose moieties have been prepared by grafting sugar derivatives onto the fullerene core and assayed as inhibitors of FimH, a bacterial adhesin, using isothermal titration calorimetry, surface plasmon resonance and hemagglutination assays.

Graphical abstract: The functional valency of dodecamannosylated fullerenes with Escherichia coli FimH—towards novel bacterial antiadhesives

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Article information


Submitted
17 Oct 2010
Accepted
28 Oct 2010
First published
22 Nov 2010

Chem. Commun., 2011,47, 1321-1323
Article type
Communication

The functional valency of dodecamannosylated fullerenes with Escherichia coli FimH—towards novel bacterial antiadhesives

M. Durka, K. Buffet, J. Iehl, M. Holler, J. Nierengarten, J. Taganna, J. Bouckaert and S. P. Vincent, Chem. Commun., 2011, 47, 1321
DOI: 10.1039/C0CC04468G

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