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Issue 4, 2011
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The functional valency of dodecamannosylated fullerenes with Escherichia coli FimH—towards novel bacterial antiadhesives

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Abstract

Fullerene hexakis-adducts bearing 12 peripheral mannose moieties have been prepared by grafting sugar derivatives onto the fullerene core and assayed as inhibitors of FimH, a bacterial adhesin, using isothermal titration calorimetry, surface plasmon resonance and hemagglutination assays.

Graphical abstract: The functional valency of dodecamannosylated fullerenes with Escherichia coli FimH—towards novel bacterial antiadhesives

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Publication details

The article was received on 17 Oct 2010, accepted on 28 Oct 2010 and first published on 22 Nov 2010


Article type: Communication
DOI: 10.1039/C0CC04468G
Citation: Chem. Commun., 2011,47, 1321-1323
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    The functional valency of dodecamannosylated fullerenes with Escherichia coli FimH—towards novel bacterial antiadhesives

    M. Durka, K. Buffet, J. Iehl, M. Holler, J. Nierengarten, J. Taganna, J. Bouckaert and S. P. Vincent, Chem. Commun., 2011, 47, 1321
    DOI: 10.1039/C0CC04468G

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