Dual MRI-SPECT agent for pH-mapping†
Abstract
A new dual MRI/SPECT pH-responsive agent where the SPECT active moiety acts as reporter of the concentration making it possible to exploit the responsiveness of the MRI probe.
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* Corresponding authors
a
Department of Chemistry IFM and Molecular Imaging Center, University of Torino, Via Nizza 52, Torino, Italy
E-mail:
silvio.aime@unito.it
Fax: +390116706487
Tel: +390116706451
b Advanced Accelerator Applications (AAA), St. Genis Pouilly, France
c DiSCAFF, Università del Piemonte Orientale “A. Avogadro”, Via Bovio 6, 28100 Novara, Italy
d Institute for Health and Consumer Protection Joint Research Centre, European Commission Cyclotron, Via Fermi, 2749 I-21020 Ispra (VA), Italy
e University of Torino, Nucl Med Serv, Azienda Osped San Giovanni Battista, Dipartimento Med Interna Corso Bramante 88, I-10126 Torino, Italy
A new dual MRI/SPECT pH-responsive agent where the SPECT active moiety acts as reporter of the concentration making it possible to exploit the responsiveness of the MRI probe.
E. Gianolio, L. Maciocco, D. Imperio, G. B. Giovenzana, F. Simonelli, K. Abbas, G. Bisi and S. Aime, Chem. Commun., 2011, 47, 1539 DOI: 10.1039/C0CC03554H
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