Issue 1, 2011
From the journal:

Chemical Communications

Improved Cope-type hydroamination reactivity of hydrazine derivatives†‡

Francis Loiseau,a   Christian Clavette,a   Michaël Raymond,a   Jean-Grégoire Roveda,a   Alishya Burrella  and  André M. Beauchemin*a  

* Corresponding authors

a Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie-Curie, Ottawa, Canada
E-mail: andre.beauchemin@uottawa.ca
Fax: +1 613-562-5170
Tel: +1 613-562-5800, ext. 2245

Abstract

A systematic investigation on the metal-free, Cope-type hydroamination reactivity of hydrazides and analogues is reported. Optimization of the hydrazide structure resulted in more facile intramolecular reactivity and enabled intermolecular reactions of alkenes, thus providing a direct approach to polysubstituted hydrazides.

Graphical abstract: Improved Cope-type hydroamination reactivity of hydrazine derivatives

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Article information

DOI
https://doi.org/10.1039/C0CC02403A
Article type
Communication
Submitted
06 Jul 2010
Accepted
06 Sep 2010
First published
06 Oct 2010

Chem. Commun., 2011,47, 562-564

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Improved Cope-type hydroamination reactivity of hydrazine derivatives

F. Loiseau, C. Clavette, M. Raymond, J. Roveda, A. Burrell and A. M. Beauchemin, Chem. Commun., 2011, 47, 562 DOI: 10.1039/C0CC02403A

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