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Issue 1, 2011
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Improved Cope-type hydroamination reactivity of hydrazine derivatives

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Abstract

A systematic investigation on the metal-free, Cope-type hydroamination reactivity of hydrazides and analogues is reported. Optimization of the hydrazide structure resulted in more facile intramolecular reactivity and enabled intermolecular reactions of alkenes, thus providing a direct approach to polysubstituted hydrazides.

Graphical abstract: Improved Cope-type hydroamination reactivity of hydrazine derivatives

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Article information


Submitted
06 Jul 2010
Accepted
06 Sep 2010
First published
06 Oct 2010

Chem. Commun., 2011,47, 562-564
Article type
Communication

Improved Cope-type hydroamination reactivity of hydrazine derivatives

F. Loiseau, C. Clavette, M. Raymond, J. Roveda, A. Burrell and A. M. Beauchemin, Chem. Commun., 2011, 47, 562
DOI: 10.1039/C0CC02403A

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