Jump to main content
Jump to site search

Issue 6, 2011
Previous Article Next Article

Construction of an ultrahigh strength hydrogel with excellent fatigue resistance based on strong dipole–dipole interaction

Author affiliations

Abstract

A high strength hydrogel was fabricated by one-step copolymerization of dipole–dipole interaction-containing monomer, acrylonitrile, super-hydrophilic comonomer, 2-methacryloyloxyethyl phosphorylcholine and crosslinker, polyethylene glycol diacrylate (Mn = 575, PEGDA575). This dipole–dipole reinforced (DDR) hydrogel demonstrated intriguing combinations of properties such as withstanding several MPa tensile stress, tens of MPa compressive strength, excellent fatigue resistance and no yielding during tensile tests. The equilibrium water content and transparency of DDR hydrogels could be tuned by varying monomer concentration and monomer ratio. The gels exhibited low cytotoxicity and antifouling characteristic. Biodegradable high strength hydrogel could also be constructed by merely replacing PEGDA575 with bioreducible crosslinker. The method reported here offers a general strategy to design biocompatible high-strength hydrogels for tissue engineering scaffolds by copolymerizing monomer containing dipole–dipole pairing with other hydrophilic monomer.

Graphical abstract: Construction of an ultrahigh strength hydrogel with excellent fatigue resistance based on strong dipole–dipole interaction

Back to tab navigation

Supplementary files

Article information


Submitted
06 Oct 2010
Accepted
06 Dec 2010
First published
01 Feb 2011

Soft Matter, 2011,7, 2825-2831
Article type
Paper

Construction of an ultrahigh strength hydrogel with excellent fatigue resistance based on strong dipole–dipole interaction

T. Bai, P. Zhang, Y. Han, Y. Liu, W. Liu, X. Zhao and W. Lu, Soft Matter, 2011, 7, 2825
DOI: 10.1039/C0SM01108H

Social activity

Search articles by author

Spotlight

Advertisements