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Issue 2, 2011
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Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

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Abstract

A continuous-flow palladium-catalyzed amination reaction was made possible through efficient handling of solids via acoustic irradiation. Various diarylamines were obtained with reaction times ranging from 20 s to 10 min.

Graphical abstract: Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

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Supplementary files

Article information


Submitted
16 Oct 2010
Accepted
18 Nov 2010
First published
03 Dec 2010

Chem. Sci., 2011,2, 287-290
Article type
Edge Article

Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

T. Noël, J. R. Naber, R. L. Hartman, J. P. McMullen, K. F. Jensen and S. L. Buchwald, Chem. Sci., 2011, 2, 287
DOI: 10.1039/C0SC00524J

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