Jump to main content
Jump to site search

Issue 8, 2011
Previous Article Next Article

Two-photon ratiometric sensing of Hg2+ by using cysteine functionalized Ag nanoparticles

Author affiliations

Abstract

We have demonstrated a novel two-photon sensing strategy to detect mercury ions with high selectivity and sensitivity. This sensing approach is based on the observation that addition of Hg2+ into a cysteine functionalized Ag nanoparticle solution could significantly enhance their two-photon emission. An enhancement factor of up to 100 fold was obtained when mercury was added. A detection limit of as low as 65 nM could be achieved. The sensitivity and sensing range can be easily tuned. Compared to the conventional colorimetric or extinction spectrum based methods, this scheme offers improved sensitivity, quantitative detection of Hg2+ with a larger dynamic range, and allows detection deep into biological environments such as cells and tissues where deep penetration is required. The sensitivity could be further improved by using two-photon microscopy with the additional advantages of 3D detection and mapping.

Graphical abstract: Two-photon ratiometric sensing of Hg2+ by using cysteine functionalized Ag nanoparticles

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Apr 2011, accepted on 25 May 2011 and first published on 13 Jul 2011


Article type: Paper
DOI: 10.1039/C1NR10396B
Nanoscale, 2011,3, 3316-3320

  •   Request permissions

    Two-photon ratiometric sensing of Hg2+ by using cysteine functionalized Ag nanoparticles

    C. Jiang, Z. Guan, S. Y. Rachel Lim, L. Polavarapu and Q. Xu, Nanoscale, 2011, 3, 3316
    DOI: 10.1039/C1NR10396B

Search articles by author

Spotlight

Advertisements