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Issue 3, 2011
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An enzyme-sensitive probe for photoacoustic imaging and fluorescence detection of protease activity

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Abstract

A gold nanocage and dye conjugate has been demonstrated for use with photoacoustic imaging and fluorescence detection of protease activity. The detection sensitivity could be maximized by using gold nanocages with a localized surface plasmon resonance peak away from the emission peak of the dye. These hybrids can be potentially used as multimodal contrast agents for molecular imaging.

Graphical abstract: An enzyme-sensitive probe for photoacoustic imaging and fluorescence detection of protease activity

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Article information


Submitted
16 Nov 2010
Accepted
07 Dec 2010
First published
11 Jan 2011

Nanoscale, 2011,3, 950-953
Article type
Communication

An enzyme-sensitive probe for photoacoustic imaging and fluorescence detection of protease activity

X. Xia, M. Yang, L. K. Oetjen, Y. Zhang, Q. Li, J. Chen and Y. Xia, Nanoscale, 2011, 3, 950
DOI: 10.1039/C0NR00874E

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