Jump to main content
Jump to site search

Issue 7, 2011
Previous Article Next Article

Equilibrium study on the interaction of phytic acid with polyamines and metal ions

Author affiliations

Abstract

Interaction of phytic acid (myo-inositolhexakisphosphoric acid, IP) and polyamines (A = en, tn, Put, dien, 2,3-tri, 3,3-tri, Spd, 3,3,3-tet, spermine(Spm)) have been studied by potentiometric and 31P-NMR techniques. The non-covalent interactions have led to the formation of stable molecular complexes of (IP)Hn(A) type at the 1 : 1 molar ratio of the ligands, but of different numbers of protons. The IP protonation constants, stability constants of the molecular complexes and metal (Mg2+) complexes have been determined. The structural and pH dependences of stability constants showed the interactions between IP and A have the acid–base character determining their effectiveness, although the IP structure (5ax1eq, 5eq1ax) in molecular complexes should be also taken into account. 31P NMR study showed in the presence of Spm 31P highfield shifts and high pH shift of signal broadening due to chemical exchange between 5ax1eq and 5eq1ax. The preferable binding of Spm to IP over Mg2+ in neutral pH indicated the importance of polyamine as a stabilizer of phosphate compounds.

Graphical abstract: Equilibrium study on the interaction of phytic acid with polyamines and metal ions

Back to tab navigation

Supplementary files

Publication details

The article was received on 07 Mar 2011, accepted on 03 May 2011 and first published on 07 Jun 2011


Article type: Paper
DOI: 10.1039/C1MT00031D
Metallomics, 2011,3, 735-743

  •   Request permissions

    Equilibrium study on the interaction of phytic acid with polyamines and metal ions

    A. Odani, R. Jastrzab and L. Lomozik, Metallomics, 2011, 3, 735
    DOI: 10.1039/C1MT00031D

Search articles by author

Spotlight

Advertisements